Please note: this guideline has exceeded its review date and is currently under review by specialists. Exercise caution in the use of the clinical guideline.

Valproic acid

Time to steady state: 3 days

Sampling time and target range

Pre-dose: 50-100mg/L

Comment

Metabolised in the liver. 

There is a poor correlation between level and effect. Levels should only be checked for compliance or suspected toxicity. 

 

Guideline reviewed: August 2021

Page updated: May 2022




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