Please note: this guideline has exceeded its review date and is currently under review by specialists. Exercise caution in the use of the clinical guideline.

Vancomycin
Time to steady state: 1 day (longer in renal impairment).
Sampling time and target range

Trough (end of dose interval): 10–20mg/L (15-20mg/L in severe or deep seated infection)

During continuous infusion: 20–25mg/L
Comment

For Vancomycin intermittent 'pulsed' infusion see guideline here (link only active if accessing from NHS network).  Otherwise can be found via AthenA / Antimicrobial Guidelines and Information / Antimicrobial – specific guidance / Vancomycin – pulsed infusion guidelines (non-renal patients).

For Vancomycin continuous infusion see guideline here (link only active if accessing from NHS network).  Otherwise can be found via AthenA / Antimicrobial Guidelines and Information / Antimicrobial – specific guidance / Vancomycin – continuous infusion guidelines (non-renal patients).

 

Guideline reviewed: August 2021

Page updated: May 2022




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