Procedure | Recommended Antibiotics and Comments |
Arthroplasty* and any surgery involving insertion of implant |
Cefuroxime IV 1.5g OR Flucloxacillin IV 1g + Gentamicin IV as per Gentamicin prophylactic dosing table. If penicillin allergy: Teicoplanin IV 400mg + Gentamicin IV as per Gentamicin prophylactic dosing table. *Include antibiotic impregnated cement. |
Surgery without implant (clean) |
Not recommended |
Soft tissue surgery of hand |
Not recommended |
Arthroscopy |
Not routinely recommended. If previous implant, e.g. anterior cruciate ligament reconstruction, prophylaxis as per arthroplasty. |
Open fracture Open reduction Internal fixation Hemiarthroplasty* |
Flucloxacillin IV 1g + Gentamicin IV as per Gentamicin prophylactic dosing table. OR Cefuroxime IV 1.5g If penicillin allergy: Teicoplanin IV 400mg + Gentamicin IV as per Gentamicin prophylactic dosing table. *Include antibiotic impregnated cement. |
Contaminated hand trauma (without bite) incision and drainage** |
Flucloxacillin IV 2g four times daily If penicillin allergy: Vancomycin IV (as per treatment guidelines) **Treatment NOT prophylaxis. Assess severity and follow NHS Ayrshire & Arran infection management guidelines. Remember appropriate IV to oral switch and minimum 7 days in total. |
Contaminated hand trauma (with human or animal bite) incision and drainage** |
Co-amoxiclav IV 1.2g three times daily If penicillin allergy: Metronidazole IV 500mg / oral 400mg three times daily and Doxycycline oral 200mg on day one, 100mg twice daily thereafter. **Treatment NOT prophylaxis. Assess severity and follow NHS Ayrshire & Arran infection management guidelines. Remember appropriate IV to oral switch and minimum 7 days in total. |
Guideline reviewed | March 2024 |
Page updated | September 2024 |