First line:

Flucloxacillin oral 250-500 mg 6 hourly

If true penicillin / beta-lactam allergy or suspected MRSA:

Doxycycline oral 200mg stat, then 100mg once daily

N.B. In pregnant patients, doxycycline is contraindicated. See here for an alternative option in penicillin allergic pregnant patients. If pregnant with suspected MRSA, discuss with a microbiologist.

Consider surgical site infection if there is spreading cellulitis around the wound, the wound is dehiscing, there is increased swelling or tenderness, or there is worsening or purulent discharge from the wound. If there is any suspicion of a deep infection, the patient should be referred for assessment by a surgeon and consideration for admission.