Ciprofloxacin oral 500mg (1 hour prior to procedure)

Percutaneous nephrolithotomy

Endoscopic ureteric stone fragmentation / removal

Transurethral resection of the prostate (TURP)

Clean-contaminated surgery (opening of urinary tract)

Gentamicin IV as per Gentamicin prophylactic dosing table.

Gentamicin IV as per Gentamicin prophylactic dosing table

OR

Ciprofloxacin oral 500mg (1 hour prior to procedure)

Clean-contaminated surgery (use of bowel segments or manipulation of bowel)

Urethroplasty (without free flap)

Radical prostatectomy

Metronidazole IV 500mg + Gentamicin IV as per Gentamicin prophylactic dosing table.

Co-amoxiclav IV 1.2g

If penicillin allergy: Metronidazole IV 500mg + Gentamicin IV as per Gentamicin prophylactic dosing table.

Metronidazole IV 500mg + Gentamicin IV as per Gentamicin prophylactic dosing table.

Continue amoxicillin oral 500mg + metronidazole oral 400mg every 8 hours for up to 72 hours post op.

If penicillin allergy: Clarithromycin oral 500mg every 12 hours + metronidazole oral 400mg every 8 hours.

Not routinely recommended

Gentamicin IV as per Gentamicin prophylactic dosing table for large / necrotic tumours.

Cystoscopy, urodynamic examination

Clean, open and laparoscopic urological surgery

Not recommended

Not routinely recommended

Consider Metronidazole IV 500mg + Gentamicin IV as per Gentamicin prophylactic dosing table if high risk.

Flucloxacillin IV 1g

If penicillin allergy: Teicoplanin IV 400mg